Re-establish the optimal balance of your eyes with TREHAPAN^®

VISUfarma are launching TREHAPAN^® eye drops: a unique, balanced and effective combination of unique ingredients to protect,  hydrate, repair & re-generate the ocular surface for all dry eye patients that is preservative free, phosphate free and contact lens friendly.^1-3 

Dry Eye 

Dry eye is a multifactorial disease of the ocular surface characterised by loss of homeostasis of the ocular surface, accompanied by ocular symptoms, in which tear film instability, hyperosmolarity, ocular surface inflammation and damage, and neurosensory abnormalities play etiological roles.⁴ It can be attributed to a variety of factors, including dry, heated or air-conditioned environments, auto-immune diseases (such as Sjogren Syndrome, rheumatoid arthritis, and lupus), and the prolonged exposure to screens including smart phones and laptops.⁵ 

The prevalence of dry eye disease is difficult to estimate as there is no defined diagnostic test. Although it can affect people of any age, it is more prevalent in women and those over the age of 50.^5,6 It is reported that 33% of people aged 65 years or over have dry eye disease, though this is likely to be an underestimation of the true prevalence.⁶ 

Introducing TREHAPAN^® Eye Drops

Re-establish the optimal balance of your eyes with TREHAPAN^®. A unique combination of Trehalose 3%, Hyaluronic Acid 0.15% and D-Panthenol 2%, TREHAPAN^® protects, hydrates, repairs and re-generates the ocular surface for all dry eye patients.^1-3   

TREHAPAN^® eye drops is preservative & phosphate free and is suitable to use with contact lenses.¹ 

Benefits of TREHAPAN^®: 

• A unique combination of 3 unique ingredients to re-establish the optimal balance of your eyes.¹ 

• Provides long-lasting comfort with a longer residence time on the ocular surface.¹ 

• Helps keep the ocular surface hydrated and protects the corneal cells from apoptosis.^1,7,8 

• Supports homeostasis by restoring the osmotic balance of the ocular surface.^9,10 

• Has protective and anti-inflammatory properties.^1,11 

• Improves hydration and stabilises the epidermal barrier function.¹  

• Accelerates the healing of postoperative wounds.^1-3 

• Provides intense hydration of the eyes.¹ 

• Longer-lasting comfort.¹ 

• Preservative free.¹ 

• Phosphate free.¹ 

• Contact lens friendly.¹ 

• 3 drops per day.¹ 

• Remains sterile for up to 3 months after opening.¹ 

TREHAPAN^® is available in a 10ml multidose bottle and is available from all major optical wholesalers now. For more information, please call VISUfarma on 0113 4680661 or e-mail UKcustomerservices@visufarma.com  

About VISUfarma  

VISUfarma is a pan-European ophthalmic specialty pharmaceutical company with a clear mission: to bring global innovation to European eye health. Our promise is to offer high quality products and to spread eye health innovation and knowledge, from across the globe, throughout Europe. 

References 

1. TREHAPAN^® Instructions for Use (IFU). 
2. Proksch E, et al. Topical use of dexpanthenol: a 70th anniversary Article. JOURNAL OF DERMATOLOGICAL TREATMENT. 2017;28(8):766–773.  
3. Szumny D and Misiuk-Hojlo M. Dexpanthenol in the treatment of corneal disorders and injuries. Opthatherapy. Vol.9 / Nr3 (35)/2022 (195-199). 
4. TFOS DEWS II Definition and Classification Report. Ocul Surf. 2017 Jul;15(3):276-283. 
5. NHS https://www.nhs.uk/conditions/dry-eyes/ last accessed March 2024. 
6. NICE https://www.nice.org.uk/guidance/ta369/documents/dry-eye-disease-ciclosporin-final-scope2 last accessed March 2024. 
7. Luyck J, et al. Trehalose: an intriguing disaccharide with potential for medical application in ophthalmology. Clin ophtalmol. 2011;5:577–581. 
8. Elbein AD, et al. New insights on trehalose: a multifunctional molecule. Glycobiology. 2003;13(4):17-27. 
9. McDonald M. Trehalose & Eye Care. A Molecule Poised to Revolutionize Ocular Surface Care. Rev of Ophthlamol. 2018. 
10. Iturriaga G, et al. Trehalose metabolism: from osmoprotection to signaling. Int J Mol Sci. 2009;10(9):3793-3810. 
11. Li-Mei W, et al. Anti-inflammatory and Anti-oxidative Effects of Dexpanthenol on Lipopolysaccharide Induced Acute Lung Injury in Mice. Inflammation. 2016; 39:1757–1763.